Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication.
However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions.
Published online: January 30, 2002 Issue release date: February 2002 Number of Print Pages: 2 Number of Figures: 0 Number of Tables: 0 ISSN: 1660-8151 (Print) e ISSN: 2235-3186 (Online) For additional information: https:// Published online: January 30, 2002 Issue release date: February 2002 Number of Print Pages: 2 Number of Figures: 0 Number of Tables: 0 ISSN: 1660-8151 (Print) e ISSN: 2235-3186 (Online) For additional information: https:// Copyright: All rights reserved.
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Airflow was measured with nasal and oral pressure transducer and capillary oxygen was measured by finger pulse oximetry.
Sleep stages were scored from 1 to 4 using the Rechtshaffen and Kales criteria [ 8 ] with arousals scored using the American Sleep Disorders Association (ASDA) criteria [ 9 ].
Prior to polysomnography, the patients answered standardized questionnaires, with the assistance of a physician, regarding their medication use (number and class of antihypertensive drugs; use of benzodiazepines; drugs for pharmacologic treatment of Parkinson's disease), sleep disturbances, snoring, subjective sleep quality, daytime fatigue, pre-existing illnesses and surgery.
Serum creatinine was determined with a standardized serum creatinine assay.
This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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SA was defined as the respiratory disturbance index (RDI) (CKD 3).